Returning to our daily routine involves a number of changes that can take their toll on the body

Boost your immune system to get back to your daily routine

After the holidays, the immune system can be affected by changes to your routine, sleep patterns and diet.

BY Mariona Fernández | 16 September 2026

The immune system is a complex network of natural defences that extends throughout the body. It is made up of cells, tissues and organs that work together to protect our health. These include the spleen, the tonsils and the bone marrow, as well as the skin – the body’s main defence barrier and its largest organ.  

When this mechanism functions in a balanced way, it acts as a natural shield, protecting us against viruses, bacteria and cellular changes that could lead to illness. It is capable of detecting and eliminating these threats before they cause internal damage. Conversely, when it is out of balance, we become more vulnerable and are more likely to feel tired and depressed or to fall ill frequently – a condition known as "having low defences".

Returning to our routine after the holidays can be one of the causes of this imbalance. Changes to our timetables, sleep patterns and diet can prevent our defences from responding optimally. Therefore, knowing how to look after the immune system is key to coping with post-holiday stress with energy and a sense of well-being. 

 

How does the immune system work?

The immune system activates when it detects antigens – that is, invading agents that the body does not recognise as its own. 

As well as protecting us against infections, research has shown that the immune system also plays an important role in fighting cancer. The Cancer Research Institute explains that there is a treatment called immunotherapy which boosts the natural ability of the immune system to recognise and destroy cancer cells.

This defence network consists of two subsystems that work in coordination:

Innate immune system

This is our body’s rapid, general defence mechanism. It provides immediate protection against the most common pathogens that enter the body. It is also known as the non-specific immune system and includes mechanisms such as the skin, tears, nasal mucus and the cough reflex, which help to prevent the entry and spread of microorganisms.

 

Adaptive immune system

This refers to acquired immunity, that is, the protection the body develops over time against certain pathogens. This system learns from previous infections and continually adapts to recognise and combat new viruses and bacteria more effectively.

 

Holidays can disrupt our immune system

Returning to our daily routine involves a number of changes that can take their toll on the body:

  • Changes to our timetables that disrupt our biological rhythms.
  • Increased stress and changes to our sleep patterns.
  • Changes to our diet following summer’s overindulgence or irregular meals.
  • Greater exposure to respiratory viruses due to returning to work and school and changes in temperature.

The body usually gives warning signs when it is out of balance. You may feel more tired, have less energy or catch colds and other minor infections more frequently. When these signs appear, it may be a good time to review your habits and help your immune system regain its balance.

Five habits to look after your immune system as you get back into a routine

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